LAMTOR5 CLIA Kit for Pig(Sus scrofa) | EIAab.comLAMTOR5 CLIA Kit for Pig(Sus scrofa)

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LAMTOR5 (Gene name),

Ragulator complex protein LAMTOR5 (Protein name ), LTOR5_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

LAMTOR5;

Protein name:

Ragulator complex protein LAMTOR5;

Alternative:

Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5;

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Homodimer (Probable). Part of the Ragulator complex composed of LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4 and LAMTOR5. LAMTOR4 and LAMTOR5 form a heterodimer that interacts, through LAMTOR1, with a LAMTOR2, LAMTOR3 heterodimer. The Ragulator complex interacts with both the mTORC1 complex and heterodimers constituted of the Rag GTPases RRAGA, RRAGB, RRAGC and RRAGD; regulated by amino acid availability. Interacts with phosphorylated BIRC5; the resulting complex binds pro-caspase-9, as well as active caspase-9, but much less efficiently.

Function:

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway.

Subcellular Location:

Cytoplasm Lysosome

Protein Attributes:

Sequence length:

Sequence:

50:

91:

QAAKLTSDPT | DIPVVCLESD | NGNIMIQKHD | GITVAVHKMA | S

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q66X52

UniGene:

Ssc.26583

Uniprot:

Q66X52

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ELISA Kit for Pig Ragulator complex protein LAMTOR5

Cat.:

E1313h

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Packing:

96T

ELISA Kit for Pig Ragulator complex protein LAMTOR5

Cat.:

E1313b

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Packing:

96T

ELISA Kit for Pig Ragulator complex protein LAMTOR5

Cat.:

E1313m

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Packing:

96T

ELISA Kit for Pig Ragulator complex protein LAMTOR5

Cat.:

E1313p

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Packing:

96T

CLIA Kit for Pig Ragulator complex protein LAMTOR5

Cat.:

U1313b

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Pig Ragulator complex protein LAMTOR5

Cat.:

U1313h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Pig Ragulator complex protein LAMTOR5

Cat.:

U1313p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Pig Ragulator complex protein LAMTOR5

Cat.:

U1313m

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MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Pig Ragulator complex protein LAMTOR5

Cat.:

P1313Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig Ragulator complex protein LAMTOR5

Cat.:

P1313Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig Ragulator complex protein LAMTOR5

Monoclonal Antibody for Pig Ragulator complex protein LAMTOR5

Protein for Pig Ragulator complex protein LAMTOR5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Differentially expressed genes (DEGs) in porcine MII oocytes."
Cui X.S. , Jin Y.X. , Hwang K.C. , Kim N.H.
Submitted (2004-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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